Severe Bone and Muscle Pain with Bisphosphonates

A recent FDA article describes severe pain associated with two bisphosphonate drugs: Fosamax (alendronate sodium) and Actonel (risedronate sodium). The article, which was published in the Archives of Internal Medicine, describes over a hundred reports received by the FDA of severe bone, joint and muscle pain in patients being treated with Fosamax for osteoporosis. Many patients were unable to walk, climb stairs, or perform usual activities, and some of them became bedr

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